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The detection of microalbuminuria (from 30 to 300 mg/day) indicates the presence of diabetic nephropathy. The definition of glomerular filtration rate has a similar meaning. An increase in glomerular filtration rate indicates an increase in pressure in the vessels of the kidneys, which indirectly indicates the presence of diabetic nephropathy.

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The clinical stage of the disease is characterized by the appearance of a significant amount of protein in the urine, arterial hypertension, damage to the vessels of the eye with the development of visual impairment and a progressive persistent decrease in the glomerular filtration rate. The glomerular filtration rate decreases on average by 1 ml / min every month. Stage V of the disease is diagnosed when the glomerular filtration rate decreases to buy azipro online than 10 ml/min.

Prevention of damage to the renal vessels in diabetes mellitus. This is possible while maintaining the optimal level of blood glucose due to the competent prescription of hypoglycemic drugs.

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Treatment of diabetic nephropathy. All measures for the treatment of azipro pills nephropathy are divided into 3 stages. In the presence of microalbuminuria, it is also a priority to maintain a normal blood sugar level, as well as the treatment of arterial hypertension, which often occurs already at this stage of the disease. Angiotensin-converting enzyme (ACE) inhibitors, such as enalapril, in small doses are considered optimal drugs for the treatment of high blood pressure. In addition, a special diet with a maximum protein content of not more than 1 g per 1 kg of body weight is of great importance.

When proteinuria appears, the main goal of treatment is to prevent a rapid decline in kidney function and the development of end-stage renal failure. The diet introduces more stringent restrictions on the protein content in food. 0.7-0.8 g per 1 kg of body weight. With a low protein content in food, the breakdown of the body's own proteins can occur. Therefore, with a substitution purpose, it is possible to prescribe ketone analogues of amino acids, for example, ketosteril. Maintaining an optimal blood glucose level and correcting high blood pressure remains relevant. Calcium channel blockers (amlodipine) or beta-blockers (bisoprolol) are added to ACE inhibitors. With edema, diuretic drugs (furosemide, indapamide) are prescribed and the volume of fluid drunk is controlled - about 1 liter per day.